Pumping shear-sensitive crystals to centrifuges in the pharmaceutical industry

Why are Discflo Pumps ideally suited for pumping Shear-sensitive Crystals?

Disc pumps are unique in that they do not use centrifugal force or positive displacement. Instead, they operate on the boundary layer/viscous drag forces that produce a laminar flow with no pulsation[

This is significant for two reasons:

  1. Firstly, laminar flow conditions provide the best protection for shear-sensitive crystals and delicate pharmaceutical products. Non-impingement and laminar flow pumping has almost zero impact on the product.
  2. Secondly, laminar flow means lower NPSHr. Disc Pumps have NPSH requirements that are about half to a third of that required by conventional pumps plus the curve is stable through to shut off.

To re-enforce the low-shear attribute of the Discflo pump, it has actually been used in a demonstration to pump live fish.

Disc Pumps have proven ideal for a range of pharmaceutical applications, including:

  • Centrifuge feed
  • Crystal slurries
  • Solvents
  • Emulsions
  • Filter press
  • Abrasive slurries
  • Thixotropic Fluids
  • Dilatant fluids.

Customers using Discflo pumps on pumping Shear Sensitive crystals to centrifuges have reported a yield improvement as the pump does not smash the crystals and produce fines. If you have a Shear Sensitive Slurry application you would like to discuss, please contact ESI

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